SLC2A14

Protein-coding gene in the species Homo sapiens
SLC2A14
Identifiers
AliasesSLC2A14, GLUT14, SLC2A3P3, solute carrier family 2 member 14
External IDsOMIM: 611039; MGI: 95757; HomoloGene: 89200; GeneCards: SLC2A14; OMA:SLC2A14 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for SLC2A14
Genomic location for SLC2A14
Band12p13.31Start7,812,512 bp[1]
End7,891,148 bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for SLC2A14
Genomic location for SLC2A14
Band6 F2|6 57.82 cMStart122,704,768 bp[2]
End122,778,599 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • left adrenal gland

  • blood

  • bone marrow

  • bone marrow cells

  • monocyte

  • placenta

  • tibial nerve

  • gallbladder

  • urinary bladder
Top expressed in
  • spermatocyte

  • primitive streak

  • spermatid

  • seminiferous tubule

  • yolk sac

  • blood

  • superior cervical ganglion

  • otic placode

  • subiculum

  • substantia nigra
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • transmembrane transporter activity
  • glucose transmembrane transporter activity
  • transporter activity
  • D-glucose transmembrane transporter activity
Cellular component
  • integral component of membrane
  • membrane
  • nucleus
  • plasma membrane
Biological process
  • carbohydrate transport
  • multicellular organism development
  • cell differentiation
  • glucose transmembrane transport
  • transmembrane transport
  • spermatogenesis
  • transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

144195

20527

Ensembl

ENSG00000173262

ENSMUSG00000003153

UniProt

Q8TDB8

P32037

RefSeq (mRNA)
NM_001286233
NM_001286234
NM_001286235
NM_001286236
NM_001286237

NM_153449

NM_011401

RefSeq (protein)
NP_001273162
NP_001273163
NP_001273164
NP_001273165
NP_001273166

NP_703150

NP_035531

Location (UCSC)Chr 12: 7.81 – 7.89 MbChr 6: 122.7 – 122.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 2 (facilitated glucose transporter), member 14 is a protein that in humans is encoded by the SLC2A14 gene.[5]

Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane proteins that transport hexoses such as glucose and fructose into all mammalian cells. GLUTs show tissue and cell-type specific expression.[6][5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173262 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003153 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: Solute carrier family 2 (facilitated glucose transporter), member 14". Retrieved 2011-10-23.
  6. ^ Wu X, Freeze HH (December 2002). "GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms". Genomics. 80 (6): 553–7. doi:10.1006/geno.2002.7010. PMID 12504846.

Further reading

  • Joost HG, Bell GI, Best JD, Birnbaum MJ, Charron MJ, Chen YT, Doege H, James DE, Lodish HF, Moley KH, Moley JF, Mueckler M, Rogers S, Schürmann A, Seino S, Thorens B (April 2002). "Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators". American Journal of Physiology. Endocrinology and Metabolism. 282 (4): E974-6. doi:10.1152/ajpendo.00407.2001. PMID 11882521.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
  • Na+/Ca2+ exchanger
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
  • Na+-dependent ascorbic acid transporter
(24):
  • Na+/(Ca2+-K+) exchanger
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
  • basolateral iron transporter
SLC41–48
(41):
(42):
(43):
  • Na+-independent, system-L like amino-acid transporter
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter, Cotransporter
  • Na+/K+,Cl
  • Na+/Pi3
  • Na+/Cl
  • Na+/glucose
  • Na+/I
  • Cl/K+
Antiporter (exchanger)
  • Na+/H+
  • Na+/Ca2+
    • Na+/(Ca2+-K+) - Cl/HCO
      3
      (Band 3)
  • Cl-formate
  • Cl-oxalate
see also solute carrier disorders


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