Ornithine translocase

solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
Identifiers
SymbolSLC25A15
Alt. symbolsORNT1, HHH
NCBI gene10166
HGNC10985
OMIM603861
RefSeqNM_014252
UniProtQ9Y619
Other data
LocusChr. 13 q14
Search for
StructuresSwiss-model
DomainsInterPro

Ornithine translocase is responsible for transporting ornithine from the cytosol into the mitochondria in the urea cycle. It is highly expressed in the liver and pancreas.

Pathology

A disorder is associated with ornithine translocase deficiency, and a form of hyperammonemia.

See also

  • Translocase

External links

  • ornithine+translocase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  • SLC25A15 human gene location in the UCSC Genome Browser.
  • SLC25A15 human gene details in the UCSC Genome Browser.
  • v
  • t
  • e
Membrane proteins, carrier proteins: membrane transport proteins solute carrier (TC 2A)
By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
  • Na+/Ca2+ exchanger
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
  • Na+-dependent ascorbic acid transporter
(24):
  • Na+/(Ca2+-K+) exchanger
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
  • basolateral iron transporter
SLC41–48
(41):
(42):
(43):
  • Na+-independent, system-L like amino-acid transporter
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter, Cotransporter
  • Na+/K+,Cl−
  • Na+/Pi3
  • Na+/Cl−
  • Na+/glucose
  • Na+/I−
  • Cl−/K+
Antiporter (exchanger)
  • Na+/H+
  • Na+/Ca2+
    • Na+/(Ca2+-K+) - Cl−/HCO−
      3       (Band 3)
  • Cl−-formate
  • Cl−-oxalate
see also solute carrier disorders


Stub icon

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e