Epicillin
Chemical compound
- J01CA07 (WHO)
- (2S,5R,6R)-6-[[(2R)-2-Amino-2-(1-cyclohexa-1,4-dienyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- 26774-90-3 Y
- 71392
- 64486 N
- 3LU1L73C8Y
- DTXSID60181288
- Interactive image
- O=C(O)[C@@H]2N3C(=O)[C@@H](NC(=O)[C@@H](C/1=C/C\C=C/C\1)N)[C@H]3SC2(C)C
InChI
- InChI=1S/C16H21N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-4,7,9-11,14H,5-6,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1 N
- Key:RPBAFSBGYDKNRG-NJBDSQKTSA-N N
Epicillin (INN) is a penicillin antibiotic. It is not approved by the FDA for use in the United States.[citation needed]
It is an aminopenicillin.[1][2]
References
- ^ Bergan T (1979). "Studies on aminopenicillin developments. Proceedings of a symposium. Concluding remarks". Infection. 7 (Suppl 5): S507-512. doi:10.1007/bf01659785. PMID 389828. S2CID 46974138.
- ^ Mombelli G (May 1981). "[Aminopenicillin: when, how, what kind?]". Schweizerische Medizinische Wochenschrift (in German). 111 (18): 641–5. PMID 7244588.
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(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases)
Glycopeptides Lipoglycopeptides |
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Lipopeptides |
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Polymyxins |
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Other |
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- Inhibit PG subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
- Hydrolyze NAM-NAG
- Tyrothricin
- Isoniazid#
- Teixobactin
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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