CAMK2D |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e1/Protein_CAMK2D_PDB_2VN9.png/250px-Protein_CAMK2D_PDB_2VN9.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2VN9, 2W2C, 2WEL, 3GP2 |
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Identifiers |
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Aliases | CAMK2D, CAMKD, calcium/calmodulin dependent protein kinase II delta |
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External IDs | OMIM: 607708; MGI: 1341265; HomoloGene: 55561; GeneCards: CAMK2D; OMA:CAMK2D - orthologs |
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Gene location (Human) |
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![Chromosome 4 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/04/Ideogram_human_chromosome_4.svg/300px-Ideogram_human_chromosome_4.svg.png) | Chr. | Chromosome 4 (human)[1] |
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| Band | 4q26 | Start | 113,418,054 bp[1] |
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End | 113,761,927 bp[1] |
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Gene location (Mouse) |
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![Chromosome 3 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Ideogram_house_mouse_chromosome_3.svg/260px-Ideogram_house_mouse_chromosome_3.svg.png) | Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 G1- G2 | Start | 126,389,951 bp[2] |
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End | 126,639,975 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - myocardium of left ventricle
- lateral nuclear group of thalamus
- cardiac muscle tissue of right atrium
- middle temporal gyrus
- Brodmann area 23
- right ventricle
- entorhinal cortex
- tibialis anterior muscle
- deltoid muscle
- endothelial cell
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| Top expressed in | - anterior amygdaloid area
- neural layer of retina
- lobe of cerebellum
- cerebellar vermis
- lateral septal nucleus
- medial geniculate nucleus
- dorsomedial hypothalamic nucleus
- atrium
- lateral hypothalamus
- ventral tegmental area
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - kinase activity
- ATP binding
- protein kinase activity
- titin binding
- transferase activity
- protein homodimerization activity
- protein binding
- nucleotide binding
- sodium channel inhibitor activity
- calmodulin-dependent protein kinase activity
- protein serine/threonine kinase activity
- transmembrane transporter binding
- calmodulin binding
- identical protein binding
| Cellular component | - endocytic vesicle membrane
- membrane
- sarcoplasmic reticulum membrane
- plasma membrane
- nucleoplasm
- sarcoplasmic reticulum
- sarcolemma
- neuron projection
- nucleus
- cytoplasm
- cytosol
- calcium channel complex
| Biological process | - regulation of heart contraction
- interferon-gamma-mediated signaling pathway
- regulation of transcription by RNA polymerase II
- regulation of membrane depolarization
- positive regulation of cardiac muscle hypertrophy
- protein phosphorylation
- cellular response to calcium ion
- regulation of cardiac muscle cell action potential involved in regulation of contraction
- regulation of histone deacetylase activity
- regulation of cellular localization
- negative regulation of sodium ion transmembrane transport
- phosphorylation
- regulation of the force of heart contraction
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
- regulation of ryanodine-sensitive calcium-release channel activity
- negative regulation of sodium ion transmembrane transporter activity
- MAPK cascade
- protein complex oligomerization
- regulation of cell growth
- regulation of cellular response to heat
- regulation of cell communication by electrical coupling involved in cardiac conduction
- regulation of heart rate by cardiac conduction
- nervous system development
- cell differentiation
- regulation of cell communication by electrical coupling
- positive regulation of cardiac muscle cell apoptotic process
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
- peptidyl-serine phosphorylation
- peptidyl-threonine phosphorylation
- endoplasmic reticulum calcium ion homeostasis
- protein autophosphorylation
- relaxation of cardiac muscle
- cardiac muscle cell contraction
- regulation of cardiac muscle cell action potential
- regulation of relaxation of cardiac muscle
- regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001221 NM_172114 NM_172115 NM_172127 NM_172128
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NM_172129 NM_001321566 NM_001321567 NM_001321568 NM_001321569 NM_001321570 NM_001321571 NM_001321572 NM_001321573 NM_001321574 NM_001321575 NM_001321576 NM_001321577 NM_001321578 NM_001321579 NM_001321580 NM_001321581 NM_001321582 NM_001321583 NM_001321584 NM_001321585 NM_001321586 NM_001321587 NM_001321588 NM_001321589 NM_001321590 NM_001321591 NM_001321592 NM_001396964 NM_001396965 NM_001396966 NM_001396967 NM_001399855 NM_001399856 NM_001399857 NM_001399858 NM_001399859 NM_001399860 NM_001399861 NM_001399862 NM_001399863 NM_001399864 NM_001399865 |
| NM_001025438 NM_001025439 NM_001293663 NM_001293664 NM_001293665
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NM_001293666 NM_023813 NM_001346635 NM_001346636 |
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RefSeq (protein) | NP_001212 NP_001308495 NP_001308496 NP_001308497 NP_001308498
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NP_001308499 NP_001308500 NP_001308501 NP_001308502 NP_001308503 NP_001308504 NP_001308505 NP_001308506 NP_001308507 NP_001308508 NP_001308509 NP_001308510 NP_001308511 NP_001308512 NP_001308513 NP_001308514 NP_001308515 NP_001308516 NP_001308517 NP_001308518 NP_001308519 NP_001308520 NP_001308521 NP_742112 NP_742113 NP_742125 NP_742126 NP_742127 |
| NP_001020609 NP_001020610 NP_001280592 NP_001280593 NP_001280594
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NP_001280595 NP_001333564 NP_001333565 NP_076302 |
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Location (UCSC) | Chr 4: 113.42 – 113.76 Mb | Chr 3: 126.39 – 126.64 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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