Bone morphogenetic protein 8A
Protein-coding gene in the species Homo sapiens
| BMP8A | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | BMP8A, entrez:353500, bone morphogenetic protein 8a, OP-2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | MGI: 104515 HomoloGene: 135983 GeneCards: BMP8A | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Bone morphogenetic protein 8A (BMP8A) is a protein that in humans is encoded by the BMP8A gene.[5]
BMP8A is a polypeptide member of the TGFβ superfamily of proteins. It, like other bone morphogenetic proteins (BMPs), is involved in the development of bone and cartilage. BMP8A may be involved in epithelial osteogenesis. It also plays a role in bone homeostasis. It is a disulfide-linked homodimer.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000183682 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032726 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: bone morphogenetic protein 8a".
External links
- Human BMP8A genome location and BMP8A gene details page in the UCSC Genome Browser.
Further reading
- Davila S, Froeling FE, Tan A, et al. (2010). "New genetic associations detected in a host response study to hepatitis B vaccine". Genes Immun. 11 (3): 232–8. doi:10.1038/gene.2010.1. PMID 20237496. S2CID 11183658.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
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| Ligand of ACVR or TGFBR | |
|---|---|
| Ligand of BMPR |
(Activin, BMP, family)
| TGFBR1: | |
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| TGFBR2: | |
| TGFBR3: |
- Cerberus
- Chordin
- Decorin
- Follistatin
- Gremlin
- Lefty
- LTBP1
- Noggin
- PARN
- THBS1
 | This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it. |
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