| FCGR2B |
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| Наявні структури |
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| PDB | Пошук ортологів: PDBe RCSB |
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| Список кодів PDB | | 2FCB, 3WJJ,%%s3WJL | | |
| Ідентифікатори |
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| Символи | FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2, Fc fragment of IgG receptor IIb, FcRII-c, FCGR2C |
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| Зовнішні ІД | OMIM: 604590 MGI: 95499 HomoloGene: 2974 GeneCards: FCGR2B |
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| Онтологія гена |
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| Молекулярна функція | • GO:0001948, GO:0016582 protein binding
• IgG binding
• amyloid-beta binding
• low-affinity IgG receptor activity
• GO:0032403 protein-containing complex binding
• transmembrane signaling receptor activity
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| Клітинна компонента | • integral component of membrane
• клітинна мембрана
• мембрана
• integral component of plasma membrane
• external side of plasma membrane
• dendritic spine
• cell body
• цитоплазма
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| Біологічний процес | • GO:0022415 viral process
• GO:0046730, GO:0046737, GO:0046738, GO:0046736 імунна відповідь
• GO:0072468 сигнальна трансдукція
• regulation of immune response
• negative regulation of type I hypersensitivity
• negative regulation of antibody-dependent cellular cytotoxicity
• follicular dendritic cell activation
• mature B cell differentiation involved in immune response
• follicular B cell differentiation
• immune complex clearance by monocytes and macrophages
• negative regulation of dendritic cell antigen processing and presentation
• regulation of B cell antigen processing and presentation
• negative regulation of immunoglobulin production
• regulation of adaptive immune response
• negative regulation of acute inflammatory response to antigenic stimulus
• positive regulation of humoral immune response
• negative regulation of humoral immune response mediated by circulating immunoglobulin
• рецептор-опосередкований ендоцитоз
• phagocytosis, engulfment
• defense response
• inflammatory response
• response to bacterium
• regulation of signaling receptor activity
• immunoglobulin mediated immune response
• antigen processing and presentation of exogenous peptide antigen via MHC class II
• cerebellum development
• negative regulation of B cell proliferation
• negative regulation of interleukin-10 production
• Fc-gamma receptor signaling pathway involved in phagocytosis
• negative regulation of macrophage activation
• negative regulation of cytotoxic T cell degranulation
• regulation of innate immune response
• mast cell activation
• positive regulation of JNK cascade
• negative regulation of phagocytosis
• positive regulation of phagocytosis
• negative regulation of immune response
• negative regulation of B cell receptor signaling pathway
• negative regulation of B cell activation
• cellular response to molecule of bacterial origin
• regulation of immune complex clearance by monocytes and macrophages
• positive regulation of neuron death
• negative regulation of neutrophil activation
• regulation of dendritic spine maintenance
• cellular response to amyloid-beta
• positive regulation of response to endoplasmic reticulum stress
• negative regulation of dendritic cell differentiation
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| Джерела:Amigo / QuickGO | |
| Ортологи |
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| Види | Людина | Миша |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (мРНК) | | NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001 |
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| RefSeq (білок) | NP_001002273
NP_001002274
NP_001002275
NP_001177757
NP_003992
| | NP_963857 |
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| Локус (UCSC) | Хр. 1: 161.66 – 161.68 Mb | Хр. 1: 170.79 – 170.8 Mb |
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| PubMed search | [1] | [2] |
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| Вікідані |
| Див./Ред. для людей | Див./Ред. для мишей |
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