Arilformamidaza

Arilformamidaza
Identifikatori
EC broj3.5.1.9
CAS broj156229-75-3
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IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
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Arilformamidaza (EC 3.5.1.9, kinureninska formamidaza, formilaza, formilkinureninaza, formilkinureninska formamidaza, formamidaza I, formamidaza II) je enzim sa sistematskim imenom aril-formilamin amidohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

N-formil-L-kinurenin + H2O {\displaystyle \rightleftharpoons } format + L-kinurenin

Ovaj enzim takođe deluje na druge aromatične formilamine.

Reference

  1. ^ Hayaishi, O. & Stanier, R.Y. (1951). „The bacterial oxidation of tryptophan. III. Enzymatic activities of cell-free extracts from bacteria employing the aromatic pathway”. J. Bacteriol. 62: 691—709. PMID 14907621. 
  2. ^ Jakoby, W.B. (1954). „Kynurenine formamidase from Neurospora”. J. Biol. Chem. 207: 657—663. PMID 13163050. 
  3. ^ Mehler, A.H. & Knox, W.E. (1950). „The conversion of tryptophan to kynurenine in liver. II. The enzymatic hydrolysis of formylkynurenine”. J. Biol. Chem. 187: 431—438. PMID 14794728. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
  • William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

  • Arylformamidase на US National Library of Medicine Medical Subject Headings (MeSH)
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Hidrolaze: ugljenično-azotne nepeptidne (EC 3.5)
3.5.1: Linearni amidi /
Amidohidrolaze3.5.2: Cyclic amides/
Amidohidrolaze3.5.3: Linear amidines/
Ureohidrolaze3.5.4: Cyclic amidines/
Aminohidrolaze3.5.5: Nitrili/
Aminohidrolaze3.5.99: Drugi
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Teme
Tipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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