ZFP64

Protein-coding gene in the species Homo sapiens
ZFP64
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

1X5W, 2DMD

Identifiers
AliasesZFP64, ZNF338, ZFP64 zinc finger protein
External IDsOMIM: 618111; MGI: 107342; HomoloGene: 7604; GeneCards: ZFP64; OMA:ZFP64 - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for ZFP64
Genomic location for ZFP64
Band20q13.2Start52,051,663 bp[1]
End52,204,308 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for ZFP64
Genomic location for ZFP64
Band2 H3|2 88.99 cMStart168,735,251 bp[2]
End168,797,507 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • germinal epithelium

  • gingival epithelium

  • secondary oocyte

  • palpebral conjunctiva

  • parietal pleura

  • endothelial cell

  • visceral pleura

  • hair follicle

  • epithelium of esophagus

  • lactiferous duct
Top expressed in
  • yolk sac

  • Rostral migratory stream

  • placenta

  • female urethra

  • fossa

  • endocardial cushion

  • condyle

  • embryo

  • epiblast

  • embryo
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • DNA binding
  • protein binding
  • metal ion binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
  • RNA polymerase II core promoter sequence-specific DNA binding
Cellular component
  • nucleus
  • histone methyltransferase complex
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
  • regulation of gene expression
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55734

22722

Ensembl

ENSG00000020256

ENSMUSG00000027551

UniProt

Q9NTW7

Q99KE8

RefSeq (mRNA)

NM_018197
NM_022088
NM_199426
NM_199427
NM_001319146

NM_009564
NM_001369059
NM_001370946

RefSeq (protein)
NP_001306075
NP_060667
NP_071371
NP_955458
NP_955459

NP_955459.2
NP_001306075.1

NP_033590
NP_001355988
NP_001357875

Location (UCSC)Chr 20: 52.05 – 52.2 MbChr 2: 168.74 – 168.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 64 homolog, isoforms 1 and 2 is a protein that in humans is encoded by the ZFP64 gene.[5][6]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000020256 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027551 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Mack HG, Beck F, Bowtell DD (Mar 1997). "A search for a mammalian homologue of the Drosophila photoreceptor development gene glass yields Zfp64, a zinc finger encoding gene which maps to the distal end of mouse chromosome 2". Gene. 185 (1): 11–7. doi:10.1016/S0378-1119(96)00607-5. PMID 9034307.
  6. ^ "Entrez Gene: ZFP64 zinc finger protein 64 homolog (mouse)".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
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  • 1x5w: Solution structure of the C2H2 type zinc-binding domain of human zinc finger protein 64, isoforms 1 and 2
    1x5w: Solution structure of the C2H2 type zinc-binding domain of human zinc finger protein 64, isoforms 1 and 2
  • 2dmd: Solution structure of the N-terminal C2H2 type zinc-binding domain of the Zinc finger protein 64, isoforms 1 and 2
    2dmd: Solution structure of the N-terminal C2H2 type zinc-binding domain of the Zinc finger protein 64, isoforms 1 and 2
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