USP47 |
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Identifiers |
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Aliases | USP47, TRFP, ubiquitin specific peptidase 47 |
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External IDs | OMIM: 614460; MGI: 1922246; HomoloGene: 9929; GeneCards: USP47; OMA:USP47 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 11 (human)[1] |
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| Band | 11p15.3 | Start | 11,841,423 bp[1] |
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End | 11,959,323 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 F1 | Start | 111,622,711 bp[2] |
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End | 111,710,868 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - internal globus pallidus
- endothelial cell
- secondary oocyte
- seminal vesicula
- vena cava
- corpus callosum
- biceps brachii
- periodontal fiber
- inferior olivary nucleus
- Achilles tendon
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| Top expressed in | - ciliary body
- vastus lateralis muscle
- triceps brachii muscle
- spermatid
- gastrocnemius muscle
- tibialis anterior muscle
- ankle
- spermatocyte
- temporal muscle
- sternocleidomastoid muscle
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - WD40-repeat domain binding
- peptidase activity
- hydrolase activity
- cysteine-type peptidase activity
- thiol-dependent deubiquitinase
- protein binding
- deubiquitinase activity
- cysteine-type endopeptidase activity
| Cellular component | - cytoplasm
- SCF ubiquitin ligase complex
- nucleoplasm
- cytosol
| Biological process | - ubiquitin-dependent protein catabolic process
- proteolysis
- negative regulation of apoptotic process
- cellular response to UV
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
- DNA repair
- positive regulation of cell growth
- monoubiquitinated protein deubiquitination
- base-excision repair
- negative regulation of G2/M transition of mitotic cell cycle
- negative regulation of transcription, DNA-templated
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
- cellular response to DNA damage stimulus
- protein deubiquitination
- positive regulation of canonical Wnt signaling pathway
- regulation of protein stability
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001282659 NM_017944 NM_001330208 |
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NM_133758 NM_177249 NM_001357952 |
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RefSeq (protein) | NP_001269588 NP_001317137 NP_060414 NP_001359020 NP_001359021
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NP_001359022 NP_001359023 NP_001359024 NP_001359025 NP_001359026 NP_001359027 NP_001359028 NP_001359029 NP_001359030 NP_001359031 NP_001359032 |
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NP_598519 NP_796223 NP_001344881 NP_001390423 |
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Location (UCSC) | Chr 11: 11.84 – 11.96 Mb | Chr 7: 111.62 – 111.71 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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