Sulfadicramide
Names | |
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Preferred IUPAC name N-(4-Aminobenzene-1-sulfonyl)-3-methylbut-2-enamide | |
Identifiers | |
CAS Number |
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3D model (JSmol) |
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ChEMBL |
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ECHA InfoCard | 100.003.727 |
KEGG |
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PubChem CID |
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UNII |
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CompTox Dashboard (EPA) |
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Properties | |
Chemical formula | C11H14N2O3S |
Molar mass | 254.30546 g/mol |
Pharmacology | |
S01AB03 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Sulfadicramide (marketed as Irgamid) is an anti-infective.[1]
References
- ^ Grześkowiak, E.; Partyka, D.; Simon, M.; Zgrabczyńska, M.; Wiśniewska, A. (2001). "Technology and physico-chemical evaluation of solid ocular inserts containing sulfadicramide and hyaluronic acid". Acta Poloniae Pharmaceutica. 58 (6): 453–458. PMID 12197618.
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(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor | |||||||||
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Sulfonamides (DHPS inhibitor) |
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Combinations |
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Other DHPS inhibitors |
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)
1st generation | |||||||||
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Fluoroquinolones |
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Newer non-fluorinated | |||||||||
Related (DG) |
inhibitors
Nitroimidazole derivatives | |
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Nitrofuran derivatives |
Rifamycins/ RNA polymerase | |
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Lipiarmycins |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This antiinfective drug article is a stub. You can help Wikipedia by expanding it. |
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