Melarsomine

Chemical compound

none

Identifiers

IUPAC name

Bis(2-aminoethyl) {4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl}arsonodithioite

CAS Number

128470-15-5

PubChem CID

65962

ChemSpider

59365

UNII

374GJ0S41A

KEGG

D08168^Y

CompTox Dashboard (EPA)

DTXSID40155907

Chemical and physical dataFormulaC₁₃H₂₁AsN₈S₂Molar mass428.41 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

C1=CC(=CC=C1NC2=NC(=NC(=N2)N)N)[As](SCCN)SCCN

InChI

InChI=1S/C13H21AsN8S2/c15-5-7-23-14(24-8-6-16)9-1-3-10(4-2-9)19-13-21-11(17)20-12(18)22-13/h1-4H,5-8,15-16H2,(H5,17,18,19,20,21,22)
Key:MGEOLZFMLHYCFZ-UHFFFAOYSA-N

(verify)

Melarsomine (melaminylthioarsenate) is an arsenic-based anthelmintic. In the U.S., it is marketed under the trade names Immiticide (Merial) and Diroban (Zoetis), and is approved by the FDA's Center for Veterinary Medicine for the treatment of adult heartworm (Dirofilaria immitis) infection in dogs. It is not approved for treatment in cats, or dogs in late-stage infection.^[1]^[2]

References

^ Tilley LP (2008). Manual of Canine and Feline Cardiology. Elsevier Health Sciences. pp. 194–197. ISBN 978-1-4160-2398-2.
^ Bonagura JD, Twedt DC (2013). Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. p. 2502. ISBN 978-0-323-22762-9.