Fluorexetamine

Chemical compound
Identifiers
  • 2-(ethylamino)-2-(3-fluorophenyl)cyclohexan-1-one
PubChem CID
  • 137332183
UNII
  • AN89GB52AM
CompTox Dashboard (EPA)
  • DTXSID701336920 Edit this at Wikidata
Chemical and physical dataFormulaC14H18FNOMolar mass235.302 g·mol−13D model (JSmol)
  • Interactive image
  • CCNC1(CCCCC1=O)c1cccc(F)c1
InChI
  • InChI=1S/C14H18FNO/c1-2-16-14(9-4-3-8-13(14)17)11-6-5-7-12(15)10-11/h5-7,10,16H,2-4,8-9H2,1H3
  • Key:FCETYWCLCUZFJI-UHFFFAOYSA-N

Fluorexetamine (3'-Fluoro-2-oxo-PCE, 3-FXE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects. It has reportedly been sold over the internet since around 2017, though has remained relatively uncommon.[1]

In April 2023 it was revealed by DrugsData.org that all their previously analyzed samples of fluorexetamine actually contained 2'-Fluoro-2-oxo-PCE (2-FXE, also known as CanKet) rather than 3'-Fluoro-2-oxo PCE (3-FXE). This was confirmed by a newly available reference standard for 2-FXE.[2] Similar misidentification may have occurred in other laboratories.

See also

References

  1. ^ Wallach J, Brandt SD (2018). "1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances". Handbook of Experimental Pharmacology. 252: 305–352. doi:10.1007/164_2018_148. ISBN 978-3-030-10560-0. PMID 30196446.
  2. ^ Erowid, DrugsData org /. "DrugsData.org (was EcstasyData): Test Details : Result #15191 - White Crystals, 15191". www.drugsdata.org. Retrieved 2023-12-02.


AMPARTooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
KARTooltip Kainate receptor
NMDARTooltip N-Methyl-D-aspartate receptor
  • See also: Receptor/signaling modulators
  • Metabotropic glutamate receptor modulators
  • Glutamate metabolism/transport modulators
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Group I
mGluR1Tooltip Metabotropic glutamate receptor 1
mGluR5Tooltip Metabotropic glutamate receptor 5
Group II
mGluR2Tooltip Metabotropic glutamate receptor 2
mGluR3Tooltip Metabotropic glutamate receptor 3
Group III
mGluR4Tooltip Metabotropic glutamate receptor 4
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
mGluR6Tooltip Metabotropic glutamate receptor 6
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
mGluR7Tooltip Metabotropic glutamate receptor 7
  • Antagonists: CPPG
  • MAP4
  • MMPIP
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
  • XAP044; Negative allosteric modulators: ADX71743
mGluR8Tooltip Metabotropic glutamate receptor 8
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
See also: Receptor/signaling modulators • Ionotropic glutamate receptor modulators • Glutamate metabolism/transport modulators


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