Fibrinolysis syndrome

Medical condition
Fibrinolysis syndrome
Other namesDefibrinating syndrome

Fibrinolysis syndrome is characterized by an acute hemorrhagic state brought about by inability of the blood to clot, with massive hemorrhages into the skin producing blackish, purplish swellings and sloughing.[1]: 826 

Symptoms

Hemorrhages (this includes severe bleeding of any particular area. Be it: nasal, rectal, oral, it also includes bleeding from scrapes, cuts, bruises (big bruises that do not disappear in the first two to three days).

Cause

The cause for Fibrinolysis syndrome, is the inability of the body to produce blood-coagulates to stop bleeding. What causes the body to not produce blood-coagulates are the low levels of fibrin, or therefore non-existent fibrin.[2]

Diagnosis

Treatment

See also

  • Skin lesion
  • Hemorrhage
  • Fibrin

References

  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
  2. ^ Merskey, C.; Johnson, A. J.; Kleiner, G. J.; Wom, H. (1967). "The Defibrination Syndrome: Clinical Features and Laboratory Diagnosis". Department of Medicine and the American National Red Cross Research Laboratory. 13: 528. doi:10.1111/j.1365-2141.1967.tb00762.x. PMID 6029954. S2CID 20990370. Fibrin is a non-globular protein involved in the clotting of blood.
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Cutaneous vasculitis
  • Erythema elevatum diutinum
  • Capillaritis
  • Urticarial vasculitis
  • Nodular vasculitis
Microvascular occlusion
  • Calciphylaxis
  • Cryoglobulinemic purpura/Cryoglobulinemic vasculitis
PurpuraSystemic vasculitis
  • see Template:Systemic vasculitis
Vascular malformationsUlcerLymphedema
  • see Template:Lymphatic vessel disease
Ungrouped
vascular-related
cutaneous conditions


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