2F-NENDCK

Chemical compound
2F-NENDCK
Identifiers
  • 2-(ethylamino)-2-(2-fluorophenyl)cyclohexan-1-one
CAS Number
  • 2850352-64-4 checkY
PubChem CID
  • 168323042
Chemical and physical data
FormulaC14H18FNO
Molar mass235.302 g·mol−1
3D model (JSmol)
  • Interactive image
  • CCNC1(CCCCC1=O)C2=CC=CC=C2F
InChI
  • InChI=1S/C14H18FNO/c1-2-16-14(10-6-5-9-13(14)17)11-7-3-4-8-12(11)15/h3-4,7-8,16H,2,5-6,9-10H2,1H3
  • Key:RTXKYSLDFKUESF-UHFFFAOYSA-N

2F-NENDCK (2-Fluoro-N-Ethylnordeschloroketamine, 2'-Fluoro-2-Oxo-Phenylcyclohexylethylamine, 2'-Fluoro-2-Oxo-PCE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects.

It was first identified in Australia in 2022 where it has been called 'CanKet' due to being first found in Canberra.[1][2] It has subsequently been found in Taiwan,China and New Zealand.[3][4][5]

See also

  • 2-Fluorodeschloroketamine
  • 3-Fluorodeschloroketamine
  • Fluorexetamine
  • Methoxetamine
  • N-Ethylnorketamine

References

  1. ^ Burke M (3 November 2022). "Alarm sounded after chemists discover new analogue of ketamine in Australia". Chemistry World.
  2. ^ Caldicott, David; McLeod, Malcolm (2022-10-20). "An entirely new illicit drug has been discovered by Australian chemists. Here's how they did it". The Conversation. Retrieved 2024-06-06.
  3. ^ Yen YT, Tsai YS, Su WL, Huang DY, Wu HH, Tseng SH, et al. (December 2022). "New ketamine analogue: 2-fluorodeschloro-N-ethyl-ketamine and its suggested metabolites". Forensic Science International. 341: 111501. doi:10.1016/j.forsciint.2022.111501. PMID 36274344. S2CID 252975335.
  4. ^ Wang KD, Yuan XL, Liu C, Cao FQ, Zhang YR, Liu WB, He SY (January 2023). "Identification of three novel new psychoactive substances 4F-AB-BUTINACA, AB-PHETINACA, and 2F-NENDCK". Drug Testing and Analysis. 15 (1): 115–122. doi:10.1002/dta.3359. PMID 35986510. S2CID 251693947.
  5. ^ "Ketamine analogue sold as ketamine in the Wellington region". High Alert. Retrieved 2024-06-07.
Glutamate receptor modulators
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Ionotropic glutamate receptor modulators
AMPARTooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
KARTooltip Kainate receptor
NMDARTooltip N-Methyl-D-aspartate receptor
  • See also: Receptor/signaling modulators
  • Metabotropic glutamate receptor modulators
  • Glutamate metabolism/transport modulators
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Group I
mGluR1Tooltip Metabotropic glutamate receptor 1
mGluR5Tooltip Metabotropic glutamate receptor 5
Group II
mGluR2Tooltip Metabotropic glutamate receptor 2
mGluR3Tooltip Metabotropic glutamate receptor 3
Group III
mGluR4Tooltip Metabotropic glutamate receptor 4
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
mGluR6Tooltip Metabotropic glutamate receptor 6
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
mGluR7Tooltip Metabotropic glutamate receptor 7
  • Antagonists: CPPG
  • MAP4
  • MMPIP
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
  • XAP044; Negative allosteric modulators: ADX71743
mGluR8Tooltip Metabotropic glutamate receptor 8
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
See also: Receptor/signaling modulators • Ionotropic glutamate receptor modulators • Glutamate metabolism/transport modulators


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